VOID
Sacral Nerve Modulation
in Non-Obstructive Urinary Retention
A Predictive Tool to Help in Treatment Decision-Making
VOID, a predictive tool for SNM implantation in non-obstructive urinary retention
VOID is a predictive tool that has been developped from a database of 357 patients that underwent a two-stage SNM procedure to treat non-obstructive urinary retention/slow urinary stream, in 11 French academic centers over a period of 20 years.
Four clinical and urodynamic predictive factors for implantable pulse generator (IPG) were reported after multivariate analysis :
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➜ Age, favoring younger patients OR 3.31 [95%CI 1.79; 6.14]; p<0.001
➜ Gender, favoring female OR 2.62 [95%CI 1.39; 4.92]; p=0.003
➜ Absence of peripheral nerve injury OR 2.25 [95%CI 1.07; 4.76]; p=0.033
➜ Maximal closure urethral pressure, favoring patients high pressure. OR 2.36 [95%CI 1.17; 4.74]; p=0.016
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Internal validation (bootstrapping techniques): good discrimination value (c-statistic, 0.724; 95%CI, 0.660 to 0.789) with a low optimism bias (0.013).
Be careful !
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In the absence of any external validation,
VOID cannot be used in daily clinical practice.
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External validation will be the subject of future scientific works.
Original article
Development of a predictive tool for sacral nerve modulation implantation in the treatment of non-obstructive urinary retention and/or slow urinary stream - A study from the Neuro-Urology Committee of the French Association of Urology
Jordan Nasri, Intasar Al Ashimi, Thibault Tricard, Raphael Fleury, Imad Matta, Elsa Bey, Benoit Mesnard, Sarah Gaillet, Claire Martin, Xavier Game, Caroline Thuillier, Emmanuel Chartier-Kastler, Gilles Karsenty, Marie-Aimée Perrouin-Verbe, Amelie Demeestere, Laurent Wagner, Alain Ruffion, Benoit Peyronnet, Christian Saussine, Véronique Phe, Patrick Vermersch, Stefan De Wachter, Xavier Biardeau
To download VOID (Excel sheet)